August 20, 2024

Consumer information: Alesse

What is Alesse Used For?

  • Alesse is a combination oral contraceptive (birth control pill) containing two hormones: levonorgestrel (a progestin) and ethinyl estradiol (an estrogen).
  • It is used to:
    • Prevent pregnancy.
    • Treat moderate acne in women over 14 who need contraception and have started menstruating.

How Does Alesse Work?

Alesse prevents pregnancy through three mechanisms:

  1. Prevents Ovulation: It stops the release of an egg from the ovary during your menstrual cycle.
  2. Thickens Cervical Mucus: It thickens the mucus in the cervix, making it harder for sperm to enter the uterus.
  3. Alters Uterine Lining: It changes the lining of the uterus (endometrium), making it less suitable for a fertilized egg to implant.

Effectiveness of Alesse:

  • Perfect Use: When taken correctly at the same time every day, Alesse is more than 99% effective at preventing pregnancy.
  • Typical Use: With typical use (which includes missed or late pills), the effectiveness drops slightly.
  • Alesse does not protect against sexually transmitted infections (STIs), so condoms should be used for STI protection.

Who Should NOT Take Alesse?

Alesse should not be used if you:

  • Are pregnant or suspect you are pregnant.
  • Have a history of or currently have:
  • Blood clots (e.g., deep vein thrombosis, pulmonary embolism).
  • Heart attack, stroke, or angina.
  • Liver disease or liver tumors.
  • Breast cancer or estrogen-dependent cancers.
  • Abnormal vaginal bleeding that has not been diagnosed.
  • High blood pressure that is not controlled.
  • Diabetes with complications such as vascular disease.

Warnings and Precautions:

  • Smoking significantly increases the risk of serious cardiovascular side effects, especially if you are over 35 years old. Women who use Alesse should avoid smoking.
  • Alesse may increase the risk of blood clots, stroke, and heart attack, particularly in women with predisposing conditions (e.g., hypertension, obesity).
  • You should not take Alesse if you are currently being treated with certain antiviral medications (e.g., some Hepatitis C treatments), as it may increase liver enzyme levels.

Common Side Effects:

  • Nausea and vomiting.
  • Irregular bleeding or spotting (especially in the first few months).
  • Headache (including migraines).
  • Breast tenderness or enlargement.
  • Weight changes.
  • Mood changes (such as depression or emotional fluctuations).

Serious Side Effects (Less Common):

  • Blood clots in veins or arteries (deep vein thrombosis, pulmonary embolism, stroke).
  • Heart attack or stroke.
  • Liver tumors (rare, but can be serious).
  • Breast cancer.
  • High blood pressure or worsening of existing high blood pressure.

Missed Pill Instructions:

If you miss 1 pill:

  • Take it as soon as you remember.
  • Take the next pill at your regular time (this may mean taking two pills in one day).
  • No backup contraception is required.

If you miss 2 or more pills (especially in the first week):

  • Take the most recent missed pill as soon as you remember (even if it means taking two pills in one day).
  • Continue taking the remaining pills at your usual time.
  • Use backup contraception (e.g., condoms) for the next 7 days.
  • If you miss 2 or more pills in the third week, skip the placebo pills and start a new pack immediately.

If you miss 3 or more pills in a row:

  • Take a pill as soon as you remember.
  • Use backup contraception for 7 days.
  • If you had unprotected sex, consider emergency contraception.

What to Do if You Vomit or Have Diarrhea:

  • If you vomit or have severe diarrhea within 4 hours of taking a pill, absorption may be incomplete.
  • Take another active pill as soon as possible and continue with the regular schedule.
  • Use backup contraception for 7 days after vomiting or diarrhea.

Other Important Information:

  • Starting Alesse:
    • You can start taking Alesse on the first day of your period for immediate protection.
    • If you start on another day, use backup contraception (e.g., condoms) for the first 7 days of taking Alesse.
  • Postpartum and Breastfeeding:
    • Alesse should not be used until at least 28 days postpartum if you are not breastfeeding.
    • If you are breastfeeding, Alesse can reduce milk production. Consult your doctor about alternative methods of contraception.
  • Contraceptive Effectiveness and Antibiotics:
    • Certain antibiotics (e.g., rifampin, tetracyclines) can reduce the effectiveness of Alesse. Use backup contraception when taking antibiotics.

Overdose Information:

  • Overdose symptoms may include nausea, vomiting, and vaginal bleeding.
  • There is no specific antidote; treatment is based on the symptoms. Contact a healthcare provider if an overdose occurs.

Storage:

  • Store Alesse at room temperature between 15°C and 30°C.
  • Keep it in its original packaging and protect it from light.
  • Keep out of reach of children and pets.

Non-Contraceptive Benefits:

Aside from preventing pregnancy, Alesse may also offer several health benefits, including:

  • Reduction in menstrual cramps (dysmenorrhea).
  • Decreased menstrual bleeding and regular periods, which can reduce the risk of iron-deficiency anemia.
  • Reduced risk of ovarian and endometrial cancers.
  • Improvement in acne and other androgen-related conditions.
  • Lower risk of developing ovarian cysts.

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